Recent studies have led to a renewed interest in probiotics, which are known to have a multitude of health benefits. The incorporation of probiotics alone or in food can provide a good strategy to supply dietary antioxidants and reduce damages caused by oxidation. Oxidative stress in patients with type 2 diabetes can be mitigated by probiotics. This oxidative stress defines a condition in which the prooxidant–antioxidant balance in the cell is disturbed. Ultimately this compromises cell viability. Probiotics, which are capable of colonizing the intestinal tract, are reported to improve metabolic diseases such as obesity and diabetes through the effects of their administration in the intestinal tract. Evidence has also shown that probiotic bacteria present significant antioxidant abilities both in vivo and in vitro.